Operate by Other people, which include Dickey, has shown that upsized mucin secretion while in the airways performs in A great deal the identical way, involving analogous vesicles (stuffed with mucin instead of neurotransmitters) and synaptotagmin and collaborating proteins.
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SP9 reduced mucin secretion by close to eighty% and mucus accumulation within the airways by a 3rd. Notably, it didn’t interfere with the traditional, slower mechanism that secretes a lower degree of mucin regularly to protect the lungs.
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